Estradiol enanthate

Estradiol enanthate
Systematic (IUPAC) name
	(17β)-3-hydroxyestra-1,3,5(10)-trien-17-yl heptanoate
Clinical data
Legal status	℞ (Prescription only);
Routes of; administration	IM
Identifiers
CAS Number	4956-37-0
ATC code	None
PubChem	CID: 21070
ChemSpider	19815
Synonyms	17β-Estradiol-17-heptanoate
Chemical data
Formula	C25H36O3
Molecular mass	384.552 g/mol
	SMILES O=C(O[C@H]3CC[C@H]4[C@H]2[C@@H](c1ccc(O)cc1CC2)CC[C@]34C)CCCCCC ;
	InChI InChI=1S/C25H36O3/c1-3-4-5-6-7-24(27)28-23-13-12-22-21-10-8-17-16-18(26)9-11-19(17)20(21)14-15-25(22,23)2/h9,11,16,20-23,26H,3-8,10,12-15H2,1-2H3/t20-,21-,22+,23+,25+/m1/s1 ; Key:RFWTZQAOOLFXAY-BZDYCCQFSA-N ;

Estradiol enanthate (INN, USAN), or estradiol enantate, is a synthetic ester, specifically the 17-heptanoyl ester, of the natural estrogen, estradiol.^[1]^[2] It is marketed under the brand names Anafertin, Deladroxate, Perlutan, and Topasel, which are combination formulations of estradiol enanthate and dihydroxyprogesterone acetophenide, as a once-monthly injectable hormonal contraceptive in Spain and Latin America,^[3]^[4] and has been used as such since at least the mid-1960s.^[5] A 10 mg dose of estradiol enanthate via intramuscular injection has been found to result in elevated estradiol levels for up to 31 days.^[6]

References

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