Ezlopitant
From Infogalactic: the planetary knowledge core
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| Systematic (IUPAC) name | |
|---|---|
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(2S,3S)-2-benzhydryl-N-[(5-isopropyl-2-methoxy-phenyl)methyl]quinuclidin-3-amine
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| Clinical data | |
| Legal status |
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| Routes of administration |
Oral |
| Pharmacokinetic data | |
| Excretion | Urine (32%), Feces (51%) |
| Identifiers | |
| CAS Number | 147116-64-1 |
| ATC code | none |
| PubChem | CID: 188927 |
| IUPHAR/BPS | 5751 |
| ChemSpider | 164166 |
| UNII | 3L098A8MPY  |
| ChEMBL | CHEMBL515966 |
| Chemical data | |
| Formula | C31H38N2O |
| Molecular mass | 454.65 g/mol |
Ezlopitant (CJ-11,974) is an NK1 receptor antagonist.[1][2][3] It has antiemetic and antinociceptive effects.[4][5] Pfizer was developing ezlopitant for the treatment of irritable bowel syndrome but it appears to have been discontinued.[1]
See also
- NK1 receptor antagonist
- Maropitant (tert-butyl instead of isopropyl)
References
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This drug article relating to the gastrointestinal system is a stub. You can help Wikipedia by expanding it. |
Categories:
- Chemical articles having calculated molecular weight overwritten
- Infobox drug articles without a structure image
- Chemical pages without DrugBank identifier
- Articles without KEGG source
- Articles without InChI source
- Drugs not assigned an ATC code
- Articles containing unverified chemical infoboxes
- Antiemetics
- NK1 receptor antagonists
- Quinuclidines
- Amines
- Phenol ethers
- Gastrointestinal system drug stubs
