Cirazoline
From Infogalactic: the planetary knowledge core
Names | |
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IUPAC name
2-[(2-cyclopropylphenoxy)methyl]-4,5-dihydro-1H-imidazole
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Identifiers | |
59939-16-1 | |
ChEMBL | ChEMBL13852 |
ChemSpider | 2663 |
515 | |
Jmol 3D model | Interactive image |
MeSH | Cirazoline |
PubChem | 2765 |
UNII | QK318GVY3Y |
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Properties | |
C13H16N2O | |
Molar mass | 216.279 g/mol |
Vapor pressure | {{{value}}} |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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verify (what is ?) | |
Infobox references | |
Cirazoline is a full agonist at the α1A adrenergic receptor, a partial agonist at both the α1B and α1D adrenergic receptors,[1] and a nonselective antagonist to the α2 adrenergic receptor.[2] It is believed that this combination of properties could make cirazoline an effective vasoconstricting agent.[2]
Cirazoline has also been shown to decrease food intake in rats, purportedly through activation of α1 adrenoceptors in the paraventricular nucleus in the hypothalamus of the brain.[3]
References
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