Allobarbital

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Allobarbital
Allobarbital.svg
Allobarbital ball-and-stick animation.gif
Systematic (IUPAC) name
5,5-diprop-2-enyl-1,3-diazinane-2,4,6-trione
Clinical data
Legal status
Identifiers
CAS Number 52-43-7 YesY
ATC code N05CA21 (WHO)
PubChem CID: 5842
ChemSpider 5635 YesY
UNII 8NT43GG2HA YesY
KEGG D02817 YesY
ChEMBL CHEMBL267719 YesY
Synonyms 5,5-Diallylbarbituric acid, Allobarbital
Chemical data
Formula C10H12N2O3
Molecular mass 208.214 g/mol
  • O=C1NC(=O)NC(=O)C1(C\C=C)C\C=C
  • InChI=1S/C10H12N2O3/c1-3-5-10(6-4-2)7(13)11-9(15)12-8(10)14/h3-4H,1-2,5-6H2,(H2,11,12,13,14,15) YesY
  • Key:FDQGNLOWMMVRQL-UHFFFAOYSA-N YesY
  (verify)

Allobarbital, also known as allobarbitone and branded as Cibalgine or Dial-Ciba (in combination with ethyl carbamate), is a barbiturate derivative invented in 1912 by Ernst Preiswerk and Ernst Grether working for CIBA. It was used primarily as an anticonvulsant[1] although it has now largely been replaced by newer drugs with improved safety profiles. Other uses for allobarbital included as an adjutant to boost the activity of analgesic drugs, and use in the treatment of insomnia and anxiety.

Allobarbital was never particularly widely used compared to better known barbiturates such as phenobarbital and secobarbital, although it saw more use in some European countries such as Bulgaria and Slovakia,[2] and is still used in for example Poland, but only as compound.[3]

References

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