Minaxolone
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Minaxolone (CCI-12923) is a neuroactive steroid which was developed as a general anesthetic but was withdrawn before registration due to toxicity seen with long-term administration in rats, and hence was never marketed.[1][2][3] It is a positive allosteric modulator of the GABAA receptor,[4] as well as, less potently, a positive allosteric modulator of the glycine receptor.[4][5]
See also
References
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Categories:
- Pages with reference errors
- Infobox drug articles without a structure image
- Chemical pages without DrugBank identifier
- Drugs not assigned an ATC code
- Drugs with no legal status
- General anesthetics
- Neurosteroids
- Alcohols
- Ethers
- Amines
- Ketones
- GABAA receptor positive allosteric modulators
- Glycine receptor agonists
- Nervous system drug stubs