ELF5
Lua error in Module:Infobox_gene at line 33: attempt to index field 'wikibase' (a nil value). E74-like factor 5 (ets domain transcription factor), is a gene found in both mice and humans.[1] In humans it is also called ESE2.
Function
The protein encoded by this gene is a member of an epithelium-specific subclass of the Ets transcritpion factor family. In addition to its role in regulating the later stages of terminal differentiation of keratinocytes, it appears to regulate a number of epithelium-specific genes found in tissues containing glandular epithelium such as salivary gland and prostate. It has very low affinity to DNA due to its negative regulatory domain at the amino terminus. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene.[1]
References
Further reading
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External links
- ELF5 protein, human at the US National Library of Medicine Medical Subject Headings (MeSH)
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This article incorporates text from the United States National Library of Medicine, which is in the public domain.
