Retinoid X receptor gamma

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Lua error in Module:Infobox_gene at line 33: attempt to index field 'wikibase' (a nil value). Retinoic acid receptor gamma (RXR-gamma), also known as NR2B3 (nuclear receptor subfamily 2, group B, member 3) is a nuclear receptor that in humans is encoded by the RXRG gene.[1][2]

Function

This gene encodes a member of the retinoid X receptor (RXR) family of nuclear receptors which are involved in mediating the antiproliferative effects of retinoic acid (RA). This receptor forms heterodimers with the retinoic acid, thyroid hormone, and vitamin D receptors, increasing both DNA binding and transcriptional function on their respective response elements. This gene is expressed at significantly lower levels in non-small cell lung cancer cells. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.[2]

See also

Interactions

Retinoid X receptor gamma has been shown to interact with ITGB3BP.[3]

References

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  2. ↑ 2.0 2.1 Lua error in package.lua at line 80: module 'strict' not found.
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Further reading

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This article incorporates text from the United States National Library of Medicine, which is in the public domain.



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