NFYB
Lua error in Module:Infobox_gene at line 33: attempt to index field 'wikibase' (a nil value). Nuclear transcription factor Y subunit beta is a protein that in humans is encoded by the NFYB gene.[1][2]
Function
The protein encoded by this gene is one subunit of a trimeric complex, forming a highly conserved transcription factor that binds with high specificity to CCAAT motifs in the promoter regions in a variety of genes. This gene product, subunit B, forms a tight dimer with the C subunit, a prerequisite for subunit A association. The resulting trimer binds to DNA with high specificity and affinity. Subunits B and C each contain a histone-like motif. Observation of the histone nature of these subunits is supported by two types of evidence; protein sequence alignments and experiments with mutants.[3]
Interactions
NFYB has been shown to interact with:
References
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Further reading
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External links
- NFYB protein, human at the US National Library of Medicine Medical Subject Headings (MeSH)
- FactorBook NF-YB
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
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