Doxanthrine

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Doxanthrine
Doxanthrine structure.png
Systematic (IUPAC) name
(6aS,12bR)-6a,7,8,12b-tetrahydro-6H-chromeno[3,4-c]isoquinoline-2,3-diol
Identifiers
ATC code none
PubChem CID: 15981509
ChemSpider 13112900
Chemical data
Formula C16H15NO3
Molecular mass 269.295 g/mol
  • c1ccc2c(c1)CN[C@H]3[C@H]2c4cc(c(cc4OC3)O)O
  • InChI=1S/C16H15NO3/c18-13-5-11-15(6-14(13)19)20-8-12-16(11)10-4-2-1-3-9(10)7-17-12/h1-6,12,16-19H,7-8H2/t12-,16-/m1/s1
  • Key:QDUNOUQOKOYLCH-MLGOLLRUSA-N
  (verify)

Doxanthrine is a synthetic compound which is a potent and selective full agonist for the dopamine D1 receptor.[1][2] Doxanthrine has been shown to be orally active in producing contralateral rotation in the 6-hydroxy-dopamine rat model of Parkinson's disease.[3]

References

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