Arachidonoyl serotonin

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Arachidonoyl serotonin
Arachidonoyl serotonin.svg
Names
IUPAC name
(5Z,8Z,11Z,14Z)-N-(2-(5-hydroxy-1H-indol-3-yl)ethyl)icosa-5,8,11,14-tetraenamide
Other names
N-arachidonoyl-serotonin
Identifiers
187947-37-1 N
ChEMBL ChEMBL191534 YesY
ChemSpider 8202943 YesY
Jmol 3D model Interactive image
PubChem 10027372
  • InChI=1S/C30H42N2O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-30(34)31-23-22-26-25-32-29-21-20-27(33)24-28(26)29/h6-7,9-10,12-13,15-16,20-21,24-25,32-33H,2-5,8,11,14,17-19,22-23H2,1H3,(H,31,34)/b7-6-,10-9-,13-12-,16-15- YesY
    Key: QJDNHGXNNRLIGA-DOFZRALJSA-N YesY
  • InChI=1/C30H42N2O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-30(34)31-23-22-26-25-32-29-21-20-27(33)24-28(26)29/h6-7,9-10,12-13,15-16,20-21,24-25,32-33H,2-5,8,11,14,17-19,22-23H2,1H3,(H,31,34)/b7-6-,10-9-,13-12-,16-15-
    Key: QJDNHGXNNRLIGA-DOFZRALJBN
  • O=C(CCC/C=C\C/C=C\C/C=C\C/C=C\CCCCC)NCCC1=CNC2=C1C=C(O)C=C2
Properties
C30H42N2O2
Molar mass 462.68 g·mol−1
Vapor pressure {{{value}}}
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
N verify (what is YesYN ?)
Infobox references

Arachidonoyl serotonin (N-arachidonoyl-serotonin, AA-5-HT) is an endogenous lipid signaling molecule. It was first described in 1998 as being an inhibitor of fatty acid amide hydrolase (FAAH).[1] In 2007, it was shown to have analgesic properties and to act as an antagonist of the TRPV1 receptor.[2] In 2011, it was shown to be present in the ileum and jejunum of the gastrointestinal tract and modulate glucagon-like peptide-1 (GLP-1) secretion.[3]

References

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